Padstow lies approximately 21 km south‑west of the Sydney central business district, and driving via the M5 motorway generally requires around 25 minutes. At the same time, train services offer a commute of about 46 minutes from Wynyard to Padstow Station.
The suburb recorded a population of 14,017 in the 2021 census.
Around 56.3 per cent of residents were born in Australia, with notable numbers from China (7.3 per cent), Vietnam (4.5 per cent), Lebanon (2.4 per cent), India (1.8 per cent) and New Zealand (1.7 per cent).
English alone was spoken at home by 49.2 per cent of people, while other languages included Arabic (7.8 per cent), Cantonese (7.0 per cent), Mandarin (6.5 per cent), Vietnamese (5.5 per cent) and Greek (3.3 per cent).
Religious affiliations were most commonly recorded as No Religion (25.2 per cent), Catholic (23.3 per cent), Islam (8.9 per cent), Anglican (8.0 per cent) and Eastern Orthodox (7.3 per cent).
Padstow railway station operates on the Sydney Trains East Hills line, with T8 Airport & South Line services and daily patronage averaging over 3,300 entries and exits.
Bus connectivity includes U‑Go Mobility routes such as the 927, 962, S5 and Metrobus M91 and 960, linking to One Tree Point, Bankstown, Miranda, Illawong, Menai, Parramatta and Hurstville.
Local commerce centres around the shopping precinct near Padstow Station, spanning the southern side around Howard Road and Padstow Parade, as well as additional shops along Cahors Road.
Educational facilities include multiple primary schools: Padstow North Public School, Padstow Park Public School, and St Therese Primary School, in addition to the special‑needs Caroline Chisholm School.
Recreational spaces include Playford Park and Stuart Street Reserve, supporting junior football clubs such as Padstow United and Padstow Hornets, while Padstow Bowling & Recreation Club offers synthetic greens.
Housing in Padstow is mixed but primarily comprises residential dwellings with pockets of light industrial facilities in the northern section near the M5 motorway.